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09-Feb-2020 20:29

Cancer stem cells, including those identified in the brain, breast and colon, give rise to tissue-specific cancer cells that grow out of control and form tumours.

In Sunday's issue of Nature Medicine, the Toronto researchers describe experiments in which they disarmed the BMI-1 gene, thereby stopping colon cancer stem cells from generating malignant cells.

"It's like doing a clinical trial on a human cancer without the human attached," he said.

The next step is for pharmaceutical companies to come up with BMI-1 inhibiting drugs that could be tested for safety and effectiveness in people.

"The step into the first clinical trials will be sooner than later," said Dick, a basic scientist who tests drugs but is not involved in their development.

Our nation has a strong legislative framework that guarantees the equal rights of people with disabilities.

In addition, a range of federal programs support the lives of Canadians with disabilities.

"It's like doing a clinical trial on a human cancer without the human attached," he said.The next step is for pharmaceutical companies to come up with BMI-1 inhibiting drugs that could be tested for safety and effectiveness in people."The step into the first clinical trials will be sooner than later," said Dick, a basic scientist who tests drugs but is not involved in their development.Our nation has a strong legislative framework that guarantees the equal rights of people with disabilities.In addition, a range of federal programs support the lives of Canadians with disabilities.But those therapies do not always result in permanent eradication of the malignancy.